Multivariate analyses of survival were performed by Cox proportional hazards models incorporating the prognostic factors identified in the univariate log rank test. Negative prognostic factors for head and neck cancer in the young K. Kourelis 1 , T. Tsue 1 , D. Girod 1 , O. Tawfik 2 , K. Sykes 1 , Y. Shnayder 1 Kansas University Medical Center, 1 Department of Otolaryngology and 2 Department of Pathology, Kansas City, KS, In this article, we have reviewed the outcome of the patients with pathologic … Background: Negative lymph node (NLN) count has been reported to associate with the prognosis of various cancers. Patient and methods. A prognostic factor may be defined as a measurable variable … The relationship of other prognostic factors with positive peritoneal cytology remains unclear. Once the diagnosis had been confirmed, several prognostic factors were analyzed: 1) Nuclear atypia, following the method reported by Spangler and Kass,20 using an incremental scale from 1 to 10, signifying the subjectively estimated percentage of nuclei involved; 2) The HER2 status was as follows: negative in 751 cases, 1+ in 440 cases, 2+ in 123 cases, and 3+ in 238 cases. This means that HER2-positive breast cancer has a less favourable prognosis than HER2-negative breast cancer. A high result can be interpreted as indicating the accuracy of such a statistic. both positive and negative control sections were in-cluded for each antibody. 1999 Aug 11. 53(3):598-604. negative negative negative negative positive negative age diminished reflexes pneumonia coma functional admission Score u z yes (Katz Index) functional status at 3 semi-annual inter- 2 vals post-stroke 3 0 z to determine the prognostic impor- tance of age, asso- ciated illness, ear- ly recovery & prcsence of more than one stroke (1) 138 Age at diagnosis Prognostic factors of node-negative large tumours. Prognostic factors for systemic relapses and for … No prognostic differences between the patients with N1, N2 or N3 disease subtypes (p=0.78) were detected. Prognostic factor defined as measurement taken at time of diagnosis or treatment that is associated with outcome. Goals for this study were: 1) to determine whether HPV-positive and HPV-negative OPSCCs have distinct prognostic factors, and 2) to explore the prognostic significance of sex and race in OPSCC after HPV stratification Study Design: Retrospective case series. Dutch Guillain-Barré Study Group. Yukinori Okada, had the original idea and collected and analyzed the data. Calcifications in or out of a mass were associated with most of the poor prognostic factors: high histological grade, positive EIC, negative ER status and positive HER-2/neu status . The purpose of this study was to assess the recurrence patterns and prognostic factors in LVSI-positive patients with pure endometrioid EC who have undergone systematic LN dissection and found to have negative LNs. The positive and negative predictive values (PPV and NPV respectively) are the proportions of positive and negative results in statistics and diagnostic tests that are true positive and true negative results, respectively. The X-tile program was used to determine the optimal cutoffs for NLN count. prognostic factors for short- and long-term outcomes of patients (pts) with TNBC pts treated in routine clinical practice. Triple-negative invasive ductal carcinoma in a 29-year-old white woman with multiple adverse prognostic factors includ-ing young age, Nottingham grade 3, Ki-67 proliferation rate of 86%, an axillary lymph node positive for cancer, lack of response to neoadjuvant chemotherapy, and lymphovascular invasion. Among the patients in the 2+ range for HER2, 65.2% (15/23) were positive for HER2 expression as examined by the fluores- Methods: Clinical characteristics of patients were collected from the Surveillance, Epidemiology, and End Results (SEER) database. Prognostic factors include those characteristics that will define the natural history of the disease, and predictive factors are those that will tell us whether a particular therapeutic intervention will result in a favorable outcome. Moreover, TOP2A was independently associated with DMFS in the HR+/HER2− subtype. Only N0 versus N1–3 classification was significant. positive disease to warrant adjuvant systemic therapy since, generally, a future risk of distant recurrence of 20% or greater is regarded significant enough to consider the risks of therapy. To provide further information on the clinical and pathological prognostic factors in triple-negative breast cancer (TNBC), for which limited and inconsistent data are available. Our retrospective analysis addressed prognostic factors for short- and long-term outcomes of patients (pts) with TNBC pts treated in routine clinical practice. The prognostic significance of positive peritoneal cytology in patients with early-stage endometrial cancer (Stage 1 or 2) is controversial and perhaps depends on the presence of other factors. Forty-one HIV-positive patients and 45 HIV-negative patients were identified. ... Clearly, this is a prognostic as well as predictive indicator. node-negative patients, and (2) those for which the risks and costs of adjuvant therapy outweigh the expected benefit.3 In this context, prognostic factors should be distinguished from predictive factors. HER2-positive breast cancer is more aggressive and more likely to spread than HER2-negative breast cancer. HIV-positive patients were younger, more likely to present with seizures and elevated serum LDH levels. Overall survival was 38.4% and it was significantly higher in the patients with negative margins and nodes. Therefore, we conducted this retrospective, dual-institutional study in order to shed some more light on these issues. Purpose: To analyze prognostic and predictive effects of immunohistochemical factors within a randomized study of high-dose versus standard-dose chemotherapy in high-risk breast cancer with >10 involved lymph nodes. They are also more likely to come back after treatment. Oncotarget. 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